Predo 50 ml

Predo is an injectable corticosteroid preparation for veterinary use, supplied in a 50 ml vial. Its active substance is prednisolone acetate, given by intramuscular injection for inflammatory and allergic conditions in large and small animals.

Composition

Active substance: prednisolone acetate. Prednisolone is the intermediate-potency glucocorticoid of veterinary practice — roughly four times as potent as hydrocortisone, and markedly less potent than dexamethasone or triamcinolone. That middle position is the point of it: it is strong enough for most inflammatory and allergic work while being easier to taper and less aggressive in its effect on the animal’s own adrenal function.

Indications

Prednisolone acetate is used in horses, camels, dogs and other species for:

• dermatitis, eczema and other inflammatory skin conditions;
• allergic and hypersensitivity reactions;
• arthritis and inflammatory joint pain;
• synovitis and tendon inflammation;
• immune-mediated conditions requiring suppression of the immune response.

How it works

Prednisolone acetate is an ester, which slows its release from the injection site and extends its action compared with the soluble sodium salts. The anti-inflammatory effect comes from suppressing the inflammatory cascade at the level of gene transcription — fewer inflammatory mediators produced, fewer inflammatory cells recruited, less capillary leak. The visible result is reduced swelling, heat, itching and pain.

Presentation and storage

Sterile injectable preparation, 50 ml vial, for intramuscular administration. Store in the original carton, protected from light, at the temperature given on the label. Do not freeze. Disinfect the stopper before each withdrawal and use a sterile needle and syringe. Keep out of reach of children.

Important

Intramuscular route only, unless the attending veterinarian directs otherwise. Corticosteroids mask the signs of underlying infection and should not be given until infection has been ruled out or is being treated. They raise laminitis risk in susceptible horses and ponies, affect glucose and insulin regulation, and are not suitable in late pregnancy. A course that has run for more than a few days must be tapered rather than stopped abruptly, because the animal’s own adrenal output will have been suppressed. Do not combine with a non-steroidal anti-inflammatory without veterinary direction. Prednisolone is a controlled medication under racing and competition rules and carries a detection time, and the withdrawal period stated on the label applies to animals destined for food production. This page is product information, not veterinary advice.